clinpgx-database

1# ClinPGx Database
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3## Overview
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5ClinPGx (Clinical Pharmacogenomics Database) is a comprehensive resource for clinical pharmacogenomics information, successor to PharmGKB. It consolidates data from PharmGKB, CPIC, and PharmCAT, providing curated information on how genetic variation affects medication response. Access gene-drug pairs, clinical guidelines, allele functions, and drug labels for precision medicine applications.
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7## When to Use This Skill
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9This skill should be used when:
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11- **Gene-drug interactions**: Querying how genetic variants affect drug metabolism, efficacy, or toxicity
12- **CPIC guidelines**: Accessing evidence-based clinical practice guidelines for pharmacogenetics
13- **Allele information**: Retrieving allele function, frequency, and phenotype data
14- **Drug labels**: Exploring FDA and other regulatory pharmacogenomic drug labeling
15- **Pharmacogenomic annotations**: Accessing curated literature on gene-drug-disease relationships
16- **Clinical decision support**: Using PharmDOG tool for phenoconversion and custom genotype interpretation
17- **Precision medicine**: Implementing pharmacogenomic testing in clinical practice
18- **Drug metabolism**: Understanding CYP450 and other pharmacogene functions
19- **Personalized dosing**: Finding genotype-guided dosing recommendations
20- **Adverse drug reactions**: Identifying genetic risk factors for drug toxicity
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22## Installation and Setup
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24### Python API Access
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